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Product |
14-3-3. gamma |
Antigen |
14.3.3 gamma recombinant protein of human origin. MW: 28-33kD. Cellular Localization: Cytoplasmic. |
Antigen
Species |
Human |
Catalog
Number |
0014-07B |
Quantity |
500µl |
Price |
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 |
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Reactivity
Against |
Human. |
Applications |
Suitable for use in Immunoprecipitation and Western Blot. Other applications have not been tested. |
Host |
Mouse |
Conjugate |
|
Type
of Ab |
Monoclonal |
Ab
Isotype |
IgG1.k |
Storage |
May be stored at 4°C for short-term only. For long-term storage. store at -20°C. Aliquots are stable for at least 24 months at -20°C. For maximum recovery of product. centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
Description |
14-3-3 proteins are a family of small. widely expressed. highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction. cell cycle regulation and apoptosis. including Raf. PKC. Bad. Cbl. and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. Expression of 14-3-3 gamma is higher in cells from vascular smooth muscle. skeletal and heart muscle. In Alzheimer’s disease and Down syndrome level of 14-3-3 gamma in brain increases significantly. |
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External Information for
14-3-3. gamma |
|
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Harvester |
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Bioinformatic Harvester for 14-3-3. gamma
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Genecard |
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