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Product |
14-3-3. gamma (BSA & Azide Free) |
Antigen |
14.3.3 gamma recombinant protein of human origin. |
Antigen
Species |
Human |
Catalog
Number |
0014-07BX |
Quantity |
100µl |
Price |
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 |
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Reactivity
Against |
Human |
Applications |
Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested. |
Host |
Mouse |
Conjugate |
|
Type
of Ab |
Monoclonal |
Ab
Isotype |
IgG1.k |
Storage |
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing. aliquot and add glycerol (40-50%). Freeze at-20°C or colder. Aliquots are stable for at least 24 months at-20°C. For maximum recovery of product. centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
Description |
14-3-3 proteins are a family of small. widely expressed. highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction. cell cycle regulation and apoptosis. including Raf. PKC. Bad. Cbl. and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. Expression of 14-3-3 gamma is higher in cells from vascular smooth muscle. skeletal and heart muscle. In Alzheimer’s disease and Down syndrome the level of 14-3-3 gamma in brain increases significantly. |
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External Information for
14-3-3. gamma (BSA & Azide Free) |
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