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United States Biological

PO Box 261, Swampscott
Massachusetts (MA)
United States of America
Toll Free (US, Can.): 800-520-3011

Antibody Information

Product
4E Binding Protein 1. phosphorylated (Ser65) (4E-BP1. PHAS-1) Pab Rb xHu
Antigen
Antigen Species
human
Catalog Number
0004-20
Quantity
100ul
Price
requestinfo
Reactivity Against
Hu Mo Rt
Applications
E B IP
Host
rabbit
Conjugate
Type of Ab
Polyclonal
Ab Isotype
IgG
Storage
Supplied as liquid in 10mM HEPES. pH 7.5. 150mM sodium chloride. 0.1mg/ml BSA 50% glycerol. No preservative added.
Description
4E-BP1 (also known as PHAS-1) normally binds eIF4E. inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding. activating cap-dependent translation. The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1. 4E-BP1 i

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4E Binding Protein 1. phosphorylated (Ser65) (4E-BP1. PHAS-1) Pab Rb xHu

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