Antibody Directory - 4E Binding Protein 1. phosphorylated (Thr37/46) (4E-BP1) Pab Rb xMo

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PO Box 261, Swampscott
Massachusetts (MA)
United States of America
Toll Free (US, Can.): 800-520-3011

Antibody Information


Product	4E Binding Protein 1. phosphorylated (Thr37/46) (4E-BP1) Pab Rb xMo
Antigen
Antigen Species	mouse
Catalog Number	0004-19
Quantity	100ul
Price
Reactivity Against	Mo
Applications	B
Host	rabbit
Conjugate
Type of Ab	Polyclonal
Ab Isotype	IgG
Storage	Supplied as a liquid in 10mM sodium HEPES. pH 7.5. 150mM sodium chloride. BSA. 50% glycerol.
Description	4E-BP1 (also known as PHAS-1) normally binds eIF4E. inhibiting cap-dependent translation. Hyperphosphorylation of 4E-BP1 disrupts this binding. activating cap-dependent translation (1). The PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 (2.3)

External Information for 4E Binding Protein 1. phosphorylated (Thr37/46) (4E-BP1) Pab Rb xMo

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